Recombinant Rat Gdnf

Recombinant Rat Gdnf

Glial cell-derived neurotrophic factor, also known as GDNF is a small protein that potently promotes the survival morphological differentiation of various neuronal which is encoded by the GDNF gene. Furthermore, it may also modulate local neuronal effects in distal regions of the motor neuron. In addition, GDNF is a founding member of the GDNF family of ligands (GFL) and has been shown to interact with GFRA2 and GDNF family receptor alpha 1. Recombinant rat GDNF (monomer) contains 135 amino acids residues, which is a disulfide-linked homodimer and it shares 99 % and 93 % a.a. sequence identity with mouse and human GDNF http://www.creativebiomart.net/description_388860_12.htm

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